Clos may refer to:

People

• Clos (surname)

Other uses

• CLOS, Command line-of-sight, a method of guiding a missile to its intended target

• Clos network, a kind of multistage switching network

• Clos (vineyard), a walled vineyard; used in France, Germany and California

• an alternative spelling of close in the name of a Cul-de-sac

• Common Lisp Object System (CLOS)