The core binding factor (CBF) is a group of heterodimeric transcription factors.

Core binding factors are composed of:

a non-DNA-binding CBFβ chain ()

• Human: CBFB

a DNA-binding CBFα chain ()

• Human: RUNX1, RUNX2, RUNX3

References

See also

• AI-10-49, an anti-leukemic drug under development.

External links