Damascene may refer to:

Topics directly associated with the city of Damascus in Syria:

• A native or inhabitant of Damascus

• Damascena, the territory around Damascus in Roman and Byzantine Syria

• Damascus Arabic, the local dialect of Damascus

• Damascus steel, developed for swordmaking

• "Damascene moment", the religious conversion of Paul

Animal breeds:

• Damascene (pigeon)

• Damascus goat

• John of Damascus (c. 676-749), Syrian Christian monk and priest

Materials technologies evoking the visual texture of Damascus steel:

• Damascening, of inlaying different metals into one another

• Damask, a reversible figured fabric

• Damascene patterning, a manufacturing process used to pattern copper into microchips