Ferrari used its 2L (1995cc/121in3) V12 engine in a number of models, all called 166 for the displacement of a single cylinder. Most early 166es were sports cars built for racing, though a later line of GT cars launched the company's street model line.

The following models used the 166 name:

• 1948 Ferrari 166 F2 Formula Two racer

• 1948 Ferrari 166 S racing barchetta and coupé

• 1948 Ferrari 166 SC motorcycle-fender Spyder Corsa racing roadster

• 1948 Ferrari 166 MM Mille Miglia racing barchetta and coupé

• 1949 Ferrari 166 Inter coachbuilt street coupé and cabriolet

• 1949 Ferrari 166 FL Formula Libre racer

• 1950 Ferrari 166 MM Berlinetta Le Mans racing berlinetta

• 1953 Ferrari 166 MM/53 'Mille Miglia' racing barchetta and coupé, updated for the 1953 season

• 1953 Ferrari-Abarth 166 MM/53 racing barchetta and coupé

The 1965 Dino 166 P and 1967 Dino 166 F2 a Formula Two used a 1,6L V6 engine.