Itis may refer to:

Healthcare

• Inflammation

• Postprandial somnolence (colloquially "the itis"), a state of drowsiness or lassitude following a meal

Information systems

• Integrated Taxonomic Information System, a partnership designed to provide consistent and reliable information on the taxonomy of biological species

• Integrated Transport Information System, a traffic management system in Klang Valley, Malaysia

Places

• Itis (Swedish name of Iitti), a municipality in Päijänne Tavastia, Finland

Other uses

• Itis shopping centre, a shopping centre in the district of Itäkeskus in East Helsinki, Finland

• "The Itis" (The Boondocks), the tenth episode of the Adult Swim animated television series, The Boondocks