Kallikrein-2 is a protein that in humans is encoded by the KLK2 gene. Like others in the kallikrein family, it is a protease enzyme, which means it participates in breaking bonds between amino acids in proteins and/or peptides. KLK2 is particularly associated with prostatic tissue, where it is involved in activating the related enzyme prostate-specific antigen (aka KLK3). It accomplishes this by cleaving off certain amino acids from inactive precursor of prostate-specific antigen (called proPSA).

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Further reading

External links

• The MEROPS online database for peptidases and their inhibitors: S01.161