Larry Murphy may refer to:

• Larry Murphy (criminal) (born 1966), Irish convicted rapist and suspected serial killer

• Larry Murphy (actor) (born 1972), American voice actor and comedian

• Larry Murphy (baseball) (1857–1911), Canadian former MLB outfielder

• Larry Murphy (ice hockey) (born 1961), Canadian former NHL defenceman

• Larry Murphy (hurler) (born 1972), Irish hurler

• Larry Murphy, a fictional character in the 2016 musical Dear Evan Hansen

See also

• Lawrence Murphy (disambiguation)