Lucci is a surname. Notable people with the surname include:

• Antonio Lucci (1682–1752), blessed Italian Franciscan

• Giovanni Luca Lucci (1637–1740), Italian painter

• Giovanni Ulisse Lucci (active 1717–1760s), Italian painter

• Mike Lucci (1939–2021), American football player

• Settimio Lucci, Italian professional football coach

• Susan Lucci (born 1946), American actress on All My Children

• YFN Lucci, real name Rayshawn Lamar Bennett (born 1991), American rapper, singer, and songwriter

• Rob Lucci, a character from the anime and manga series One Piece