MTX, mtx, or MtX may refer to:

Automobiles

• MTX (automobile), an automobile company in the Czech Republic

Ford MTX transmission, a 4 or 5-speed manual transaxle

• Ford MTX-75 transmission, a 5-speed transmission

Science and technology

• Memotech MTX, a series of computers

• Maitotoxin, a biotoxin produced by the dinoflagellate Gambierdiscus toxicus

• Methotrexate, a drug used to treat cancer and autoimmune diseases

Other uses

• MtX (gender)

• Microtransaction, purchasing goods with micropayments within a game

• MTX Audio, a manufacturer of audio electronics

• The Mr. T Experience, a punk rock band