Ottavio is the Italian form of Octavius. Its feminine given name version is Ottavia. Ottavio may refer to:

Given name

• Ottavio Cinquanta, the President of the International Skating Union

• Ottavio Leoni, Italian painter

• Ottavio Piccolomini, (1599–1656), Italian nobleman and general

• Ottavio Rinuccini (1562–1621), Italian composer

• Ottavio Serena (1837–1914), Italian politician and judge

Middle name

• Giuseppe Ottavio Pitoni (1657–1734), Italian composer

Fictional characters

• Don Ottavio, a character in Mozart's opera Don Giovanni

• One of the male innamorati of the commedia