Phosphatidylinositol 3-kinase regulatory subunit beta is an enzyme that in humans is encoded by the PIK3R2 gene.

A recent study on gene expression indicated that the PIK3R2 gene might have a key role in pan-cancer prognosis.

Interactions

PIK3R2 has been shown to interact with:

• CRKL

• Cbl gene,

• Epidermal growth factor,

• FYN,

• HER2/neu,

• Macrophage colony-stimulating factor, and

• PIK3CD.

Clinical relevance

PIK3R2 mutations were recently shown to be associated with polymicrogyria.

References

Further reading