Perutz is a surname. Notable people with the surname include:

• Leo Perutz (1882–1957), Czech-Austrian novelist and mathematician

• Max Ferdinand Perutz (1914–2002), Austrian-British molecular biologist

• Robin Perutz (born 1949), son of Max, chemist

• Otto Perutz (1847–1922), Czech-German chemist

See also

• Peretz