Ferroxidase also known as Fe(II):oxygen oxidoreductase is an enzyme that catalyzes the oxidization of iron II to iron III:

1. 4 Fe2+ + 4 H+ + O2 ⇔ 4 Fe3+ + 2H2O

Examples

Human genes encoding proteins with ferroxidase activity include:

• CP – Ceruloplasmin

• FTH1 – Ferritin heavy chain

• FTMT – Ferritin, mitochondrial

• HEPH - Hephaestin

References