Klaf or KLAF may refer to:

• Klaf, (or kelaf; Hebrew: ), the designation given a particular piece of skin in Talmudic tradition

• KLAF-LD, a low-power television station (channel 14, virtual 14) licensed to serve Lafayette, Louisiana, United States

• Purdue University Airport (ICAO airport code KLAF), a public-use airport in Tippecanoe County, Indiana, United States