Keratoderma is a local or general thickening of the horny layer of the epidermis.

Classification

The keratodermas are classified into the following subgroups:

Congenital

Simple keratodermas

Diffuse palmoplantar keratodermas

• Diffuse epidermolytic palmoplantar keratoderma

• Diffuse nonepidermolytic palmoplantar keratoderma

• mal de Meleda

Focal palmoplantar keratoderma

• Striate palmoplantar keratoderma

Punctate palmoplantar keratoderma

• Keratosis punctata palmaris et plantaris

• Spiny keratoderma

• Focal acral hyperkeratosis

Complex keratodermas

Diffuse palmoplantar keratoderma

• Erythrokeratodermia variabilis

• Palmoplantar keratoderma of Sybert

• Olmsted syndrome

• Naegeli–Franceschetti–Jadassohn syndrome

Focal palmoplantar keratoderma

• Papillon–Lefèvre syndrome

• Pachyonychia congenita type I

• Pachyonychia congenita type II

• Focal palmoplantar keratoderma with oral mucosal hyperkeratosis

• Camisa disease

Ectodermal dysplasias

• Clouston's hidrotic ectodermal dysplasia

• Acrokeratotic poikiloderma

• Dermatopathic pigmentosa reticularis

Syndromic keratodermas

• Vohwinkel syndrome

• Palmoplantar keratoderma associated with esophageal cancer

• Palmoplantar keratoderma and spastic paraplegia

• Naxos disease

• Striate palmoplantar keratoderma, woolly hair, and left ventricular dilated cardiomyopathy

• Keratitis-ichthyosis-deafness syndrome

• Corneodermatosseous syndrome

• Huriez syndrome

• Oculocutaneous tyrosinemia

• Cardiofaciocutaneous syndrome

• Schöpf–Schulz–Passarge syndrome

Acquired

Acquired keratodermas

• AIDS-associated keratoderma

• Arsenical keratoses

• Calluses

• Climacteric keratoderma

• Clavi (Corns)

• Eczema

• Human papillomavirus

• Keratoderma blenorrhagicum

• Lichen planus

• Norwegian scabies

• Paraneoplastic keratoderma

• Psoriasis

• Reactive arthritis

• Secondary syphilis

• Tinea pedis

• Sézary syndrome

• Tuberculosis verrucosa cutis

• Drug-induced keratoderma

See also

• Palmoplantar keratoderma

• List of cutaneous conditions

References

External links