Chromone (or 1,4-benzopyrone) is a derivative of benzopyran with a substituted keto group on the pyran ring. It is an isomer of coumarin.

Derivatives of chromone are collectively known as chromones. Most, though not all, chromones are also phenylpropanoids.

Examples

• 6,7-dimethoxy-2,3-dihydrochromone has been isolated from Sarcolobus globosus.

• Altechromone A can be isolated from fungi such as Alternaria sp.

• Eucryphin, a chromone rhamnoside, can be isolated from the bark of Eucryphia cordifolia.

• Cromolyn (disodium cromoglicate) was found to inhibit antigen challenge as well as stress induced symptoms. Cromoglicate is used as a mast cell stabilizer in allergic rhinitis, asthma and allergic conjunctivitis.

• Nedocromil sodium was found to have a somewhat longer half-life than cromolyn; however, production was discontinued in the US in 2008.

• Xanthone with a second aromatic ring.

See also

• Coumarin – a structural isomer

• Furanochromones

References

External links

• – "4-chromone"

• Synthesis at organic-chemistry.org