CACC may refer to:

• Calcium-activated chloride channel, a cellular ion signalling pathway

• Campaign against Climate Change, a UK pressure group that aims to raise public awareness of global warming through mobilising mass demonstrations

• A Canada (CA) Ministry of Health Communication Centre

• Center for Animal Care and Control, the non-profit operator of New York City's municipal shelter system

• Central Alabama Community College, a two-year institution of higher learning located in Alexander City, Alabama.

• Central Atlantic Collegiate Conference, a US intercollegiate athletic conference affiliated with the NCAA's Division II

• Citizens for Alternatives to Chemical Contamination, a Michigan environmental group

• Commercial Aircraft Corporation of China Ltd., a Chinese company manufacturing large passenger aircraft

• Commander, Air Component Command, a US military abbreviation (see 607th Air Intelligence Squadron)

• Correlated Active Clause Coverage, A Logic Coverage Criterion from Software Testing

• Cooperative Adaptive Cruise Control, an extension of Adaptive Cruise Control in which vehicles exchange information

• Chin Association for Christian Communication, a non-profit organization for Chin people in Burma.

• Cliftonville Academy Cricket Club