Four Score may refer to:

• Archaic term for 80

• Four Score, a cocktail created by Joe Gilmore

• The NES Four Score, a four-controller adapter for the NES

• "Fourscore", a 1982 piece of music composed by David Dundas, used as the original theme tune to UK television station Channel 4

• The first words of Abraham Lincoln's Gettysburg Address

• The FOUR Score (Coma Scale) (Full Outline of UnResponsiveness Score), a clinical grading scale for the assessment of level of consciousness