TLF or TlF may refer to:

• TLF (band), French rap band

• Telefol language, a Papua New Guinean language

• Timing Library Format, a type of text file

• Trésor de la langue française, a French dictionary

• The Little Foundation

• Tigrayan Liberation Front of Ethiopia

• Text Layout Framework, a software library within Adobe Flex

• Total Life Forever, an album by the British band Foals

• Thallium fluoride (chemical formula TlF)

• Taiwanese Localism Front