Tigua, Tiguex, Tigüex, Tiwan, and Tiwesh may refer to:

• Albuquerque metropolitan area, sometimes referred to as Tiguex

• Southern Tiwa language, a pueblo language group in New Mexico

• Southern Tiwa Puebloans, a pueblo people in central and northern New Mexico

• The location of the Tiguex War, in the vicinity of Albuquerque and Bernalillo, New Mexico