Spool may refer to:

• Spool (aeronautics), part of a jet engine

• Spool (record label), active 1998–2008

• Spool (software company), a social bookmarking company

• Bobbin, on which thread, yarn or wire is wound

• Cable reel, used to carry various types of electrical wires

• Emma Spool, a fictional character in the film Psycho II

• Jared Spool (born 1960), American tech writer

• Spooling, a form of multi-programming

• Spool pin, used in pin tumbler locks

• Winch

• Spool, a type of locking differential