Myosin-8, or myosin heavy chain 8, is a protein that is encoded by the MYH8 gene. Myosins are proteins found in muscle, composed of two heavy chains and two light chains.

The human MYH8 protein is 1,937 amino acids long, with a molecular mass of 222kDa.

Mutations in MYH8 are associated with Trismus pseudocamptodactyly syndrome.

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