Levene is a surname. Notable people with the surname include:

• Allan Levene (born 1949 or 1950), British-American information technology specialist and political candidate

• George Levene (1885–1930), American football player and coach at the college level

• Gus Levene (1911–1979), American composer, arranger, orchestrator, guitarist

• Gustavo Gabriel Levene (1905–1987), Argentinian historian and writer

• Harry Levene, English boxing promoter, associated with Terry Lawless

• Howard Levene (1914–2003), American statistician and geneticist

• John Levene (born 1941), English film and television actor

• Keith Levene (1957–2022), English musician

• Peter Levene (born 1941), English businessman and nobleman

• Philip Levene (1926–1973), English television writer, actor, and producer

• Phoebus Levene (1869–1940), biochemist who identified the components of DNA

• Rebecca Levene, British author

• Sam Levene (1905–1980), American stage and film actor

See also

• Levene's test, a statistical test used to assess variance between data sets

• Stora Levene, a locality in Västra Götaland County, Sweden

• Levine