Markopoulo () may refer to places in Greece:

• Markopoulo Mesogaias, a suburban town of Athens

• Markopoulo, Elis, a small village in the municipal unit of Tragano, Elis

• Markopoulo, Kefalonia, a village in the southeastern part of the island of Kefalonia

• Markopoulo Oropou, a commune in the northeastern part of Athens near Oropos

• Limin Markopoulou, or Porto Rafti, the port of Markopoulo Mesogaias