Filotti is a Romanian surname. Notable people with the surname include:

• Eugen Filotti (1896–1975), Romanian diplomat, journalist and writer

• Andrei Filotti (1930-2024), Romanian hydropower engineer.

• Ion Filotti Cantacuzino (1908–1975), Romanian film producer, film producer, writer and psychiatrist

Maria Filotti (1883–1956), Romanian actress

• Maria Filotti Theatre, theatre in Brăila, Romania