Physostigma is a genus of flowering plants in the family Fabaceae. It includes five species of erect or climbing herbs and subshrubs native to sub-Saharan Africa. They grow in tropical swamp and riverine vegetation and seasonally-dry forest, open woodland, and grassland in the Guineo-Congolian and Zambezian regions. The genus belongs to subfamily Faboideae.

Species in the genus include:

• Physostigma coriaceum Merxm.

• Physostigma cylindrospermum (Welw. ex Baker) Holmes

• Physostigma laxius Merxm.

• Physostigma mesoponticum Taub.

• Physostigma venenosum Balf.

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