IGRA or Igra may refer to:

• Indian Gaming Regulatory Act, a law governing Native American (Indian) gambling industries

• Interferon gamma release assay, a lab test used in tuberculosis diagnosis

• International Gay Rodeo Association, a sanctioning body for gay rodeos

• International Guitar Research Archive, a specialized research collection

• Igra, a rural locality (a settlement) in the Udmurt Republic, Russia

• Integrated Global Radiosonde Archive, collecting worldwide radiosonde observations.

• Meshullam Igra (–1801), Galician rabbi