arvau

Wikipedia / Leucines

The leucines are primarily the four isomeric amino acids: leucine, isoleucine, tert-leucine (terleucine, pseudoleucine) and norleucine. Being compared with the four butanols, they could be classified as butyl-substituted glycines; they represent all four possible variations.

Leucine and isoleucine belong to the proteinogenic amino acids; the others are non-natural.

Isomers

Including the stereoisomers, six further isomers could be added: D-leucine, D-isoleucine, L-alloisoleucine, D-alloisoleucine, D-tert-leucine and D-norleucine.

Leucines

Name

L-Leucine

L-Isoleucine

L-tert-Leucine (terleucine, pseudoleucine)

L-Norleucine

Other names

2-Amino-4-methylpentanoic acid,Isobutylglycine

2-Amino-3-methylpentanoic acid,sec-Butylglycine

2-Amino-3,3-dimethylbutanoic acid,tert-Butylglycine

2-Amino-hexanoic acid,n-Butylglycine

Structure

CAS-number

61-90-5

73-32-5

20859-02-3

327-57-1

PubChem

Molecular formula

C6H13NO2

Molar mass

131.18 g/mol

Derivatives

Cycloleucine could be classified as a cyclic derivative of norleucine. With a cyclopentane-ring, it has two hydrogen atoms fewer and thus is not an isomer. The α-carbon atom is not a stereocenter.

See also

Literature

  • Jeremy M. Berg, John L. Tymoczko, Lubert Stryer: Biochemie. 6 Auflage, Spektrum Akademischer Verlag, Heidelberg 2007. .

  • Donald Voet, Judith G. Voet: Biochemistry. 3. Auflage, John Wiley & Sons, New York 2004. .

  • Bruce Alberts, Alexander Johnson, Peter Walter, Julian Lewis, Martin Raff, Keith Roberts: Molecular Biology of the Cell, 5. Auflage, Taylor & Francis 2007, .

References