MI2, Mi2, Mi-2, M:i-2, or Mi 2 may refer to:

• MI2, the British Military Intelligence Section 2

• Mi2 (band), a Slovenian rock band founded in Rogatec in 1995

• Mi2 (console), a handheld game console developed and created by Dutch company Planet Interactive

• Mil Mi-2, small, lightly armed turbine-powered transport helicopter

• Mission: Impossible 2 (also M:i-2), a 2000 action spy film directed by John Woo

• Square mile (also mi), an imperial and US unit of measure for area

• Xiaomi Mi 2, an Android smartphone

• Monkey Island 2: LeChuck's Revenge, a 1991 video game