Patient zero, or the index case, is the first documented patient in a disease epidemic within a population.

Patient zero or Patient Zero may also refer to:

Arts and entertainment

• Weasel (Marvel Comics), a supervillain and an adversary of Spider-Man and Deadpool

• Patient Zero (audio drama), 2009, based on the television series Doctor Who

• Patient Zero (film), a 2018 fantasy-horror film

• "Patient Zero" (The Outer Limits), a 2001 television episode

• Patient Zero: A Joe Ledger Novel, 2009, by Jonathan Maberry

• "Patient Zero", a 2000 short story by Tananarive Due

• Patient Zero, a demoscene production by Farbrausch

• "Patient Zero", a song by Cypecore from the album Make Me Real

• "Patient Zero", a song by Hammerfall from the album Infected

• "Patient Zero", a song by Aimee Mann from the album Mental Illness

• Patient Zero, a campaign in the 2016 video game Hitman

Other uses

• Gaëtan Dugas (1952–1984), Canadian flight attendant initially labeled "Patient Zero" in the AIDS epidemic

• Killing Patient Zero, 2019 Canadian documentary about Gaëtan Dugas who became demonized as "patient zero" for HIV/AIDS

See also

• Patient 0 (Enterprise Earth album), an album (and title track) by American deathcore band Enterprise Earth

• Zero Patience, a musical about AIDS