A panic button is an electronic device designed to assist in alerting somebody (usually the Emergency Services) in emergency situations.

Panic Button may also refer to:

• Panic Button (1964 film), a comedy starring Jayne Mansfield

• Panic Button, a 2007 TV film starring Holly Marie Combs

• Panic Button (2011 film), a British horror thriller

• Panic Button (Playhouse 90), an American television play

• Panic Button Records, an American record label

• Panic Button (company), a video game development studio based in Austin, Texas

• Panic Button, a 2013 program broadcast by TruTV

• PanicButton, a Mozilla Firefox boss key