Lysophosphatidic acid receptor 3 also known as LPA3 is a protein in humans that is encoded by the LPAR3 gene. LPA3 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).

Function

This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.

Evolution

Sequence homologyParalogues

Source:

• LPAR1

• LPAR2

• S1PR1

• S1PR3

• S1PR4

• S1PR2

• S1PR5

• CNR1

• GPR3

• MC5R

• GPR6

• GPR12

• MC4R

• CNR2

• MC3R

• MC1R

• MC2R

• GPR119

See also

• Lysophospholipid receptor

References

Further reading

External links