Sphingosine-1-phosphate receptor 3 also known as S1PR3 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is also known as S1P3.

Function

This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.

Evolution

Sequence homologyParalogues to S1PR3 GeneGene

Source:

• S1PR1

• S1PR5

• S1PR2

• S1PR4

• LPAR1

• LPAR3

• LPAR2

• CNR1

• MC5R

• GPR6

• GPR12

• MC4R

• CNR2

• GPR3

• MC3R

• MC2R

• GPR119

• MC1R

See also

• Lysophospholipid receptor

References

Further reading

External links